ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

10 Type 1 Diabetes Mellitus

Continuous glucose monitoring, insulin pumps and artificial pancreas

ey0015.10-4 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.4 Revisiting the relationships between measures of glycemic control and hypoglycemia in Continuous Glucose Monitoring Data Sets

M Gimenez , AJ Tannen , M Reddy , V Moscardo , I Conget , N Oliver

To read the full abstract: Diabetes Care. 2018;41:326-332The question whether or not T1DM patients with low HbA1c levels, which are thought to characterize good metabolic control, in fact experience hypoglycemia and most importantly severe hypoglycemia more frequently than T1DM patients with high HbA1c levels and hence worse metabolic control has been discussed controversially. However, it is commonl...

ey0015.10-5 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.5 Cost-effectiveness of continuous glucose monitoring for adults with T1DM compared with self-monitoring of blood glucose: the DIAMOND randomized trial

W Wan , MR Skandari , A Minc , AG Nathan , A Winn , P Zarei , M O'Grady , ES Huang

To read the full abstract: Diabetes Care. 2018;41:1227-1234Health care is being delivered by organizations that can be regarded as representing ´health industries´. Health care providers work within complex financial constraints and frequently within for profit settings and tight financial frameworks. Hence, health provision is more and more driven by cost-effectiveness and the willingness ...

ey0015.10-6 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.6 Reduction in hypoglycemia with the predictive low-glucose management system: a long-term randomized controlled trial in adolescents with T1DM

MB Abraham , JA Nicholas , GJ Smith , JM Fairchild , BR King , GR Ambler , FJ Cameron , EA Davis , TW Jones , PLGM Study Group

To read the full abstract: Diabetes Care. 2018;41:303-310One of the major short term complications of T1DM is the imminent risk of hypoglycemia during insulin treatment. In addition and importantly, long term complications of diabetes include those induced by frequent hypoglycemia, namely neurologic and developmental impairment upon frequent hypoglycemic episodes at a young age. In addition, it is de...

ey0015.10-7 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.7 Closed-loop control during intense prolonged outdoor exercise in adolescents with T1DM: the artificial pancreas ski study

MD Breton , DR Cherñavvsky , GP Forlenza , MD DeBoer , J Robic , RP Wadwa , LH Messer , BP Kovatchev , DM Maahs

To read the full abstract: Diabetes Care. 2017;40:1644-1650Exercise is thought to lead to more stable metabolic control but may also be associated with an increased risk of hypoglycemia. The selection of sport disciplines does not differ between youngsters with diabetes and their healthy siblings. Also, patients with diabetes are not restricted in respect to their sporting activities but seem to enga...

ey0015.10-8 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.8 Association of insulin pump therapy vs insulin injection therapy with severe hypoglycemia, ketoacidosis, and glycemic control among children, adolescents, and young adults with T1DM

B Karges , A Schwandt , B Heidtmann , O Kordonouri , E Binder , U Schierloh , C Boettcher , T Kapellen , J Rosenbauer , RW Holl

To read the full abstract: JAMA. 2017;318:1358-1366Here, the authors compared the metabolic control in young patients with T1DM with insulin pump therapies versus multiple injection treatment modalities using the data from 30 579 patients younger than 20 years of age of 446 centers in a prospective population-based cohort study. While it is very clear that pump therapy, compared with injection ...

ey0015.10-10 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.10 International consensus on use of continuous glucose monitoring

T Danne , R Nimri , T Battelino , RM Bergenstal , KL Close , JH DeVries , S Garg , L Heinemann , I Hirsch , SA Amiel , R Beck , E Bosi , B Buckingham , C Cobelli , E Dassau , FJ Doyle , S Heller , R Hovorka , W Jia , T Jones , O Kordonouri , B Kovatchev , A Kowalski , L Laffel , D Maahs , HR Murphy , K Nørgaard , CG Parkin , E Renard , B Saboo , M Scharf , WV Tamborlane , SA Weinzimer , M Phillip

To read the full abstract: Diabetes Care. 2017;40:1631-1640[Comments on 10.9 and 10.10] These two publications describe guidelines made by the international learned societies on the use of continuous glucose monitoring devices. It is important to learn from these publications that education and guidance are pivotal before continuous glucose...