ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

14 Science and Medicine

Imprinting without DNA methylation

ey0015.14-8 | Imprinting without DNA methylation | ESPEYB15

14.8 Maternal H3K27me3 controls DNA methylation-independent imprinting

A Inoue , L Jiang , F Lu , T Suzuki , Y Zhang

To read the full abstract: Nature 2017;547:419Since the identification of DNA methylation as a master regulator of genomic imprinting more than 20 years ago, it has been the only known mammalian germline imprinting mark. However, recent studies have identified several imprinted genes capable of maintaining paternal allele-specific expression in the absence of oocyte DNA methylation. Here, t...