ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

2 Antenatal and Neonatal Endocrinology

Dietary composition, age, and sex determine the central inflammatory response associated with the long-term outcomes of excess weight gain

ey0015.2-18 | Dietary composition, age, and sex determine the central inflammatory response associated with the long-term outcomes of excess weight gain | ESPEYB15

Dietary composition, age, and sex determine the central inflammatory response associated with the long-term outcomes of excess weight gain

P Argente-Arizón , F Díaz , P Ros , V Barrios , M Tena-Sempere , LM García-Segura , J Argente , JA Chowen

To read the full abstract: Endocrinology. 2018 Jan 1;159(1):368-387Hypothalamic inflammation has been linked to the development and progression of obesity and its sequelae. Obesity in rodents and humans is associated with gliosis of the arcuate nucleus, a key hypothalamic region for the regulation of energy homeostasis and adiposity. Gliosis, the activation of astrocyte and microglial cell popula...