ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

2 Antenatal and Neonatal Endocrinology

Novel mechanisms of islet dysfunction in intrauterine growth restricted rats

ey0015.2-19 | Novel mechanisms of islet dysfunction in intrauterine growth restricted rats | ESPEYB15

Novel mechanisms of islet dysfunction in intrauterine growth restricted rats

CS Rashid , YC Lien , A Bansal , LJ Jaeckle-Santos , C Li , KJ Won , RA Simmons

To read the full abstract: Endocrinology. 2018 Feb 1;159(2):1035-1049Placental insufficiency leads to intrauterine growth restriction (IUGR) which in the fetus leads to hypoxemia and hypoglycemia. IUGR fetuses are charaterised by having higher circulating catecholamine concentrations and lower circulating insulin concentrations, as well as impaired glucose stimulated insulin secretion. In cases o...