ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Endocr Rev 2018;39:3,333This review is interesting for several reasons. It focuses on a specific type of cells lining the wall of the third ventricle in the median eminence of the hypothalamus. This region acts both as a secretor of neuropeptides and as a sensor of the metabolic status of the periphery. These two functions imply a bidirectional physiological pathway: br...

To read the full abstract: Nat Rev Endocrinol 2017;13:588-598Central hypothyroidism has received much interest in recent years, partly due to the discovery of new causal gene mutations. This is a comprehensive review on several aspects of central hypothyroidism. It discusses prevalence, and its variation between different countries; pitfalls in diagnosis, including assay interference; concurrent...

To read the full abstract: Nat Rev Endocrinol 2018;14:285-300This is an interesting review of the history of research in the field of GH-IGF1 and the clinical use of GH. It comprises a timeline starting in 1884 with the description of dwarfism (General Tom Thumb) and gigantism, and ending in 2015-16 describing the discovery of paternally inherited IGF2 mutations and PAPPA-2 mutations as causes f...