ISSN 1662-4009 (online)

ESPE Yearbook of Paediatric Endocrinology (2018) 15 10.18 | DOI: 10.1530/ey.15.10.18

ESPEYB15 10 Type 1 Diabetes Mellitus Psychology and quality of life (3 abstracts)

10.18 Increasing risk of psychiatric morbidity after childhood onset T1DM: a population-based cohort study

Dybdal D , Tolstrup JS , Sildorf SM , Boisen KA , Svensson J , Skovgaard AM & Teilmann GK


Department of Paediatrics and Adolescent Medicine, Nordsjællands Hospital, Hillerød, Denmark


To read the full abstract: Diabetologia. 2018;61:831-838

T1DM in childhood and adolescence is a high burden for patients and family members. This is reflected by research that shows an increased incidence of psychiatric disorders in this patient group. Especially depression, eating disorders and anxiety disorders seem to be more prevalent. However data are mainly from small cohorts or regional limited. The aim of the authors of this study was to focus on sex differences, duration of diabetes and age at diabetes onset in a national cohort from Denmark. T1DM in this analysis was associated with a two to threefold increased risk of eating disorders and a 55-95% increase in the risk of mood disorders in both sexes. The risk of personality disorders increased only in girls whereas the risk for substance-misuse was increased only in boys. In this cohort the risk increases over time with the highest risk after 5 or more years after diagnosis of diabetes. This study result implicates once more the need for diagnostic and preventive strategies regarding the elevated risk of psychiatric comorbidity.

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