ESPEYB15 10 Type 1 Diabetes Mellitus Prevention (4 abstracts)
10.19 Infant Feeding and Risk of T1DM in Two Large Scandinavian Birth Cohorts
Lund-Blix NA , Dydensborg Sander S , Størdal K , Nybo Andersen AM , Rønningen KS , Joner G , Skrivarhaug T , Njølstad PR9 , Husby S & Stene LC
Department of Pediatric Research, Oslo University Hospital, Rikshospitalet, Oslo, Norway
To read the full abstract: Diabetes Care. 2017;40:920-927
Breast feeding has been identified as one albeit weak protective factor protecting from the development of for example obesity, autoimmune disease and in particular T1DM. The mechanisms of this preventive effect are not known. One explanation might still be a confounding effect of social status, overall healthy lifestyles in the families in whom breast feeding is more prevalent or alike.
In this large cohort study from two Scandinavian cohorts, evidence is provided that supports the notion that breastfeeding reduces the risk of T1DM. However, no dose-effect was seen: among those subjects who had been breastfed, no evidence indicated that prolonging full or any breastfeeding was associated with a reduced risk of T1DM. It therefore could very well be that it is not mother´s milk or any constituent in it that is protective but any other factor associated with or related to breast feeding. Nevertheless, the data may support the concept of breastfeeding as one protective factor against T1DM. It is important to note that more research is needed as to the potential mechanism by which breast feeding may act as a protective factor against T1DM since this would eventually lead to prevention and large scale protection against the disease.
Volume 15
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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