ISSN 1662-4009 (online)

ESPE Yearbook of Paediatric Endocrinology (2018) 15 3.12 | DOI: 10.1530/ey.15.3.12

ESPEYB15 3 Thyroid Pediatric thyroid cancer (2 abstracts)

3.12 Thyroid nodules in pediatric patients: sonographic characteristics and likelihood of cancer

Richman DM , Benson CB , Doubilet PM , Peters HE , Huang SA , Asch E , Wassner AJ , Smith JR , Cherella CE & Frates MC


Department of Radiology, Brigham and Women’s Hospital, and Thyroid Program, Division of Endocrinology, Boston Children’s Hospital, Boston MA, USA


To read the full abstract: Radiology 2018:171170

Current American Thyroid Association (ATA) guidelines recommend the application of adult ultrasound criteria to classify thyroid nodules in children and adolescents1. However, few studies have evaluated the sonographic and demographic features that could predict malignancy in a large cohort of young patients with thyroid nodules.

Here, Richman et al. report the largest series so far of sonographic features of pediatric thyroid nodules/cancers. First, the study confirmed earlier results of higher rates of malignancy in thyroid nodules in pediatric patients than in adults. Second, the authors confirmed that criteria for malignancy in adults were useful in children. Further, in contrast to adults, they revealed that risk for malignancy increased with size of the nodule in the pediatric age group. In summary, these results provide a specific pediatric view on thyroid nodules, sharpening our eyes, but not changing the current criteria for indication of fine needle aspiration.

1. Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM, Dinauer CA, Hamilton J, Hay ID, Luster M, Parisi MT, Rachmiel M, Thompson GB, Yamashita S, American Thyroid Association Guidelines Task Force. Management Guidelines for children with thyroid nodules and differentiated cancer. Thyroid 2015;25:716-759.