ESPE Yearbook of Paediatric Endocrinology

Preface: This year, many new mechanisms and new concepts have been described in neuroendocrinology. Investigating physiology or pathogenic mechanisms but also developing biological markers of neuroendocrine dysfunctions in humans is very challenging. Several strategies are needed: dosage of neuropeptides in the cerebrospinal fluid, genome-wide association studies in very large population studies, classical genetic investigation in mice but also studies on invertebrates to unde...