ESPE Yearbook of Paediatric Endocrinology

Nat Rev Endocrinol. 2021 May;17(5):261–275 Abstract: https://pubmed.ncbi.nlm.nih.gov/33727709/In brief: This article systematically reviews the current advances in the understanding of mineral metabolism with focus on the regulation of mineralization in skeletal tissue and inhibition of mineralization in non-skeletal tissue. This is mandatory reading for any aspiring endocrino...

To read the full abstract: Nature 567, 43–48 (2019)Cell engineering might be a way to reinstall insulin-production in the pancreas of people with autoimmune diabetes. This experimental mouse study achieved to switch human alpha cells to secrete insulin.Cell-identity switches, in which terminally differentiated cells are converted into different cell types, rep...