ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0016.5-16 | Basic Science - Bone | ESPEYB16

5.16. Discovery of a periosteal stem cell mediating intramembranous bone formation

S Debnath , AR Yallowitz , J McCormick , S Lalani , T Zhang , R Xu , N Li , Y Liu , YS Yang , M Eiseman , JH Shim , M Hameed , JH Healey , MP Bostrom , DA Landau , MB Greenblatt

Abstract: Nature. 2018 Oct;562(7725):133–139.In brief: A newly discovered periosteal stem cell pool with features distinct from other skeletal mesenchymal stem cells (MSCs) is present in murine and human bone and reveals a pivotal function in intramembranous ossification, cortical bone architecture and fracture healing in conditional knockout mouse strains.</st...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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