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ey0015.10-23 | Therapy and interventions | ESPEYB15

10.23 Effect of financial incentives on glucose monitoring adherence and glycemic control among adolescents and young adults with T1DM: a randomized clinical trial

CA Wong , VA Miller , K Murphy , D Small , CA Ford , SM Willi , J Feingold , A Morris , YP Ha , J Zhu , W Wang , MS Patel

To read the full abstract: JAMA Pediatr. 2017;171:1176-1183Adolescence is certainly the most difficult age for reaching T1DM treatment and HbA1c goals. In this age group, most patients have deteriorated metabolic control, and higher risk for acute complications, such as severe hypoglycemia and DKA. Getting into therapeutic contact is very hard in this period of life for diabetes teams ...

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ey0019.14-6 | Steroidogenesis and beyond | ESPEYB19

14.6. Altered steroidome in women with gestational diabetes mellitus: Focus on neuroactive and immunomodulatory steroids from the 24th week of pregnancy to labor

L Ond�ejikova , A Pa�izek , P Šimjak , D Vejražkova , M Velikova , K Anderlova , M Vosatkova , H Krejči , M Koucky , R Kancheva , M Duškova , M Vaňkova , J Blunt , M Hill

Biomolecules 2021;11:1746 doi: 10.3390/biom11121746Brief summary: Comprehensive steroid profiling of pregnant women with and without gestational diabetes mellitus (GDM) during late gestation revealed specific GDM-related steroidomic changes, linking the maternal compartment to GDM pathophysiology and highlighting the interaction between GDM and the stage of gestation.It is...

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ey0016.15-15 | (1) | ESPEYB16

15.15. Irisin mediates effects on bone and fat via [alpha]V integrin receptors

H Kim , CD Wrann , M Jedrychowski , S Vidoni , Y Kitase , K Nagano , C Zhou , J Chou , VA Parkman , SJ Novick , TS Strutzenberg , BD Pascal , PT Le , DJ Brooks , AM Roche , KK Gerber , L Mattheis , W Chen , H Tu , ML Bouxsein , PR Griffin , R Baron , CJ Rosen , LF Bonewald , BM Spiegelman

To read the full abstract: Cell. 2018 Dec 13;175(7):17561768.e17.Irisin, a cytokine secreted by muscle during exercise, effects bone resorption and the differentiation of preadipocytes into thermogenic brown fat cells by displacing tethers between the cell and extracellular matrix molecules. Physical activity can reverse age-dependent decline in skeletal muscle, preventing osteopor...

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ey0015.6-15 | When should an extensive genetic investigation be performed? | ESPEYB15

6.15 Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies

MF Portnoi , MC Dumargne , S Rojo , SF Witchel , AJ Duncan , C Eozenou , J Bignon-Topalovic , SA Yatsenko , A Rajkovic , M Reyes-Mugica , K Almstrup , L Fusee , Y Srivastava , S Chantot-Bastaraud , C Hyon , C Louis-Sylvestre , P Validire , C de Malleray Pichard , C Ravel , S Christin-Maitre , R Brauner , R Rossetti , L Persani , EH Charreau , L Dain , VA Chiauzzi , I Mazen , H Rouba , C Schluth-Bolard , S MacGowan , WHI McLean , E Patin , E Rajpert-De Meyts , R Jauch , JC Achermann , JP Siffroi , K McElreavey , A Bashamboo

To read the full abstract: Hum Mol Genet. 2018 Apr 1;27(7):1228-1240See comment on 6.16...

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ESPE Yearbook of Paediatric Endocrinology

10.23 Effect of financial incentives on glucose monitoring adherence and glycemic control among adolescents and young adults with T1DM: a randomized clinical trial

14.6. Altered steroidome in women with gestational diabetes mellitus: Focus on neuroactive and immunomodulatory steroids from the 24th week of pregnancy to labor

15.15. Irisin mediates effects on bone and fat via [alpha]V integrin receptors

6.15 Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies

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