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ey0015.2-17 | Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice | ESPEYB15

Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice

L Han , C Ren , L Li , X Li , J Ge , H Wang , YL Miao , X Guo , KH Moley , W Shu , Q Wang

To read the full abstract: Nat Genet. 2018 Mar;50(3):432-442Maternal obesity is associated with poor outcomes across the reproductive spectrum including infertility, increased time to pregnancy, early pregnancy loss, congenital abnormalities and neonatal complications. Adverse effects are detectable as early as the oocyte and preimplantation embryo stage, and that these early effects may cont...

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ey0016.1-6 | New Mechanisms | ESPEYB16

1.6. Regulation of feeding by somatostatin neurons in the tuberal nucleus

SX Luo , J Huang , Q Li , H Mohammad , CY Lee , K Krishna , AM Kok , YL Tan , JY Lim , H Li , LY Yeow , J Sun , M He , J Grandjean , S Sajikumar , W Han , Y Fu

To read the full abstract: Science 2018;361:7681.The tuberal nucleus (TN) is a hypothalamic region which is well described in humans but remains poorly defined in rodents. In this paper, the authors demonstrated by specific and sophisticated techniques the role of somatostatin expressing TN (TNSST) neurons in the control of food intake in mice. Interestingly, their resul...

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ESPE Yearbook of Paediatric Endocrinology

Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice

1.6. Regulation of feeding by somatostatin neurons in the tuberal nucleus

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