ISSN 1662-4009 (online)

ey0015.3-11 | Pediatric thyroid cancer | ESPEYB15

3.11 DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma

JD Wasserman , N Sabbaghian , S Fahiminiya , R Chami , O Mete , M Acker , MK Wu , A Shlien , L de Kock , WD Foulkes

To read the full abstract: J Clin Endocrinol Metab 2018;103:2009-2015Thyroid cancer in children and adolescents has a higher rate of regional and distant metastases, and recurrence rate than in adults. However, little is known about the molecular origin of thyroid carcinoma in children. DICER1 encodes for an endoribonuclease responsible for processing RNA into s...