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ey0015.14-15 | Nurtured by our parent’s genes | ESPEYB15

14.15 The nature of nurture: Effects of parental genotypes

A Kong , G Thorleifsson , ML Frigge , BJ Vilhjalmsson , AI Young , TE Thorgeirsson , S Benonisdottir , A Oddsson , BV Halldorsson , G Masson , DF Gudbjartsson , A Helgason , G Bjornsdottir , U Thorsteinsdottir , K Stefansson

To read the full abstract: Science 2018;359:424-428This ground-breaking study shows that your genetic make-up may influence your appearance, behaviour and health risks, not only by acting directly on your biology, but also indirectly, through the effects on your parents and how they cared and “nurtured” you. Such parental effects are obvious for very early life traits, su...

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ey0016.14-16 | (1) | ESPEYB16

14.16. Insights into imprinting from parent-of-origin phased methylomes and transcriptomes

F Zink , DN Magnusdottir , OT Magnusson , NJ Walker , TJ Morris , A Sigurdsson , GH Halldorsson , SA Gudjonsson , P Melsted , H Ingimundardottir , S Kristmundsdottir , KF Alexandersson , A Helgadottir , J Gudmundsson , T Rafnar , I Jonsdottir , H Holm , GI Eyjolfsson , O Sigurdardottir , I Olafsson , G Masson , DF Gudbjartsson , U Thorsteinsdottir , BV Halldorsson , SN Stacey , K Stefansson

To read the full abstract: Nat Genet 2018;50:15421552The authors analyse whole blood samples collected in participants of the Icelandic deCODE genetics studies in order to distinguish maternal genotype versus paternal genotype effects on gene expression and methylation in blood. The results provide a new map of imprinted methylation and gene expression patterns across the human gen...

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ESPE Yearbook of Paediatric Endocrinology

14.15 The nature of nurture: Effects of parental genotypes

14.16. Insights into imprinting from parent-of-origin phased methylomes and transcriptomes

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