ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

13 Global Health for the Paediatric Endocrinologist

Advances in the Diagnosis and Management of Congenital Hypothyroidism

ey0015.13-15 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

The five papers included in this section reflect the increasing interest by resource-limited countries in developing such a program but also highlight specific points that need to be considered in countries that embark in this wonderful initiative to make it successful.

S Gowachirapant , N Jaiswal , A Melse-Boonstra , V Galetti , S Stinca , I Mackenzie , S Thomas , T Thomas , P Winichagoon , K Srinivasan , MB Zimmerman

To read the full abstract: Lancet Diabetes Endocrinol 2017; 5:853-63 This prospective, randomized trial investigates the benefits of iodine supplementation (200 mcg per day) in pregnant women from Thailand and India on the neurological development of their children. Iodine readily crosses the placenta and is required for the synthesis of thyroid hormones by the fetal thyroid gland. In add...

ey0015.13-16 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

13.16 Incidence of congenital hypothyroidism in China: data from the national newborn screening program, 2013-2015

K Deng , C He , J Zhu , J Liang , X Li , X Xie , P Yu , N Li , Q Li , Y Wang

To read the full abstract: J Pediatr Endocrinol Metab 2018; 31(6):601-608This article summarizes the findings of likely the largest program of neonatal congenital hypothyroidism (CH) screening in the world. This is a truly impressive effort. The overall incidence of CH was 1/2421, in line with other reports that also observed a relatively high incidence of CH in neonates born in Asia. However, a...

ey0015.13-17 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

13.17 Assessment of knowledge, attitudes and practices towards newborn screening for congenital hypothyroidism before and after a health education intervention in pregnant women in a hospital setting in Pakistan

B Tariq , A Ahmed , A Habib , A Turab , N Ali , SB Soofi , S Nooruddin , RJ Kumar , A Tariq , F Shaheen , S Ariff

To read the full abstract: Int Health 2018; 10(2):100-107This article addresses the important issue of acceptance of the congenital screening for congenital hypothyroidism (CH) by the population in general and the families in particular. While it is usually obvious for the health professional that screening for CH is beneficial to the potentially affected neonate, culture, level of education, ...

ey0015.13-18 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

13.18 Worldwide Recall Rate in Newborn Screening Programs for Congenital Hypothyroidism

L Mehran , D Khalili , S Yarahmadi , A Amouzegar , M Mojarrad , N Ajang , F Azizi

To read the full abstract: Int J Endocrinol Metab 2017; 15(3):e55451Systematic neonatal screening for congenital hypothyroidism (CH) was first proposed by Dr Jean Dussault, a Canadian (adult) endocrinologist, in 1974. It was rapidly implemented in most high-income countries in the late 1970’s and 1980’s. Ideally, a screening program should be highly sensitive (able to ...

ey0015.13-19 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

13.19 Newborn Screening Guidelines for Congenital Hypothyroidism in India: Recommendations of the Indian Society for Pediatric and Adolescent Endocrinology (ISPAE) - Part I: Screening and Confirmation of Diagnosis

MP Desai , R Sharma , I Riaz , S Sudhanshu , R Parikh , V Bhatia

To read the full abstract: Indian J Pediatr 2018; 85(6):440-447In 2017, the population of India was estimated at 1.28 billion. With a birth rate of 19/1000, it means that 24.4 million babies are born each year in India. More than half of the births take place at home, in particular in rural India. Assuming an incidence of 1:2500 for congenital hypothyroidism (CH), close to 10,000 babies are b...