ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Science 2018;359:1395-1399Brain development and behavior are influenced by early life experiences, such as nutrients, stress, adversity and maternal care. While we believe the epigenome is the mediator, these authors investigated whether the genome itself of individual brain cells could be changed by environmental factors. A possible mechanism relies on mo...

To read the full abstract: Development and Psychopathology 2017;29:1517-1538Work in rodents, already some years ago, showed that epigenetic changes can be transmitted trans generations. This study shows that in humans, the simple act of touching during infancy has lifelong consequences on gene expression through epigenetic changes that sustain for at least 4 years. Children who were distresse...