ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

2 Antenatal and Neonatal Endocrinology

Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice

ey0015.2-17 | Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice | ESPEYB15

Maternal obesity induces embryonic defects by affecting the levels of DPPA3 gene in mice

L Han , C Ren , L Li , X Li , J Ge , H Wang , YL Miao , X Guo , KH Moley , W Shu , Q Wang

To read the full abstract: Nat Genet. 2018 Mar;50(3):432-442Maternal obesity is associated with poor outcomes across the reproductive spectrum including infertility, increased time to pregnancy, early pregnancy loss, congenital abnormalities and neonatal complications. Adverse effects are detectable as early as the oocyte and preimplantation embryo stage, and that these early effects may cont...