ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2019

4. Growth and Growth Factors

New Therapeutic Options

ey0016.4-5 | New Therapeutic Options | ESPEYB16

4.5. The beneficial effect of combined GH/GnRHa therapy in increasing adult height outcome in children with ISS

L Lazar , S Levy , T Oron , J Meyerovitch , L de Vries , S Shalitin , A Tenenbaum , M Phillip , Y. Lebenthal

To read the full abstract: J Clin Endocrinol Metab. 2019;104:3287-3295.The current definition of idiopathic short stature (ISS) refers to a heterogeneous group of short children, in the absence of any underlying detectable cause, including both normal variants of growth and pathological conditions. ISS subjects have been reported to reach an average final height of −1.5 SDS in boys...