ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2019

7. Puberty

Clinical Guidance

ey0016.7-11 | Clinical Guidance | ESPEYB16

7.11. Gonadal function and pubertal development in patients with Silver-Russell syndrome

WJ Goedegebuure , CCJ Smeets , JS Renes , YB de Rijke , ACS Hokken-Koelega

To read the full abstract: Hum Reprod. 2018 Nov 1;33(11):2122–2130This longitudinal study of 31 patients (14 males) with Silver-Russell syndrome (SRS) and 123 non-SRS small-for-gestational-age (SGA) patients (65 males) shows that Sertoli cell dysfunction is more common in SRS males, with 11p15 loss of methylation (LOM), but gonadal function seems to be unaffected in SRS females....

ey0016.7-12 | Clinical Guidance | ESPEYB16

7.12. Prevalence of cranial MRI findings in girls with central precocious puberty: a systematic review and meta-analysis

S Cantas-Orsdemir , JL Garb , HF Allen

To read the full abstract: J Pediatr Endocrinol Metab. 2018 Jul 26;31(7):701–710.This meta-analysis assesses the prevalence of intracranial lesions in girls with central precocious puberty and hence evaluates the benefit of routine MRIs in girls with puberty onset at age 6–8 years.Central precocious puberty (CPP) is defined as the developme...

ey0016.7-13 | Clinical Guidance | ESPEYB16

7.13. High prevalence of syndromic disorders in patients with non-isolated central precocious puberty

S Wannes , M Elmaleh-Berges , D Simon , D Zenaty , L Martinerie , C Storey , G Gelwane , A Paulsen , E Ecosse , N De Roux , JC Carel , J Leger

To read the full abstract: Eur J Endocrinol. 2018 Dec 1;179(6):373–380.This observational cohort study including children followed for central precocious puberty (CPP) in a single academic centre in Paris, France, identifies a large proportion of patients with complex disorders without structural hypothalamic lesions on MRI.Patients with CPP und...

ey0016.7-14 | Clinical Guidance | ESPEYB16

7.14. Pituitary deficiency and precocious puberty after childhood severe traumatic brain injury: a long-term follow-up prospective study

Y Dassa , H Crosnier , M Chevignard , M Viaud , C Personnier , I Flechtner , P Meyer , S Puget , N Boddaert , S Breton , M Polak

To read the full abstract: Eur J Endocrinol. 2019 May 1;180(5):281–290.This longitudinal prospective study of 61 children with a 5-10 years follow-up post severe traumatic brain injury evaluates the prevalence of pituitary deficiency and precocious puberty.In children, retrospective and prospective studies report variable rates of hypothyroidism...