Clinical Trials - New Treatments | 0016 | ESPEYB16 | Yearbook of Paediatric Endocrinology 2019 | ESPE Yearbook of Paediatric Endocrinology

ey0016.8-9 | Clinical Trials - New Treatments | ESPEYB16

8.9. A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

GD Perkins , C Ji , CD Deakin , T Quinn , JP Nolan , C Scomparin , S Regan , J Long , A Slowther , H Pocock , JJM Black , F Moore , RT Fothergill , N Rees , L O'Shea , M Docherty , I Gunson , K Han , K Charlton , J Finn , S Petrou , N Stallard , S Gates , R Lall , Collaborators PARAMEDIC2

To read the full abstract: N Engl J Med. 2018; 379(8): 711721.In attempting to reduce the rate of death and disability associated with cardiac arrest worldwide, emergency medical workers have few effective treatments other than early initiation of cardiopulmonary resuscitation (CPR) and prompt defibrillation. Epinephrine (adrenaline) has potentially beneficial effects in cardiac ar...

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ey0016.8-10 | Clinical Trials - New Treatments | ESPEYB16

8.10. Treatment of Primary Aldosteronism with mTORC1 Inhibitors

B Trinh , M Hepprich , MJ Betz , T Burkard , C Cavelti-Weder , E Seelig , F Meienberg , DV Kratschmar , F Beuschlein , M Reincke , A Odermatt , MN Hall , MY Donath , MM Swierczynska

To read the full abstract: J Clin Endocrinol Metab. 2019; pii: jc.201900563.Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, affecting ~6% of the adult general hypertensive population. Patients with PA are at increased risk of cerebrovascular and cardiovascular morbidity, renal abnormalities and metabolic syndrome. The activity of mTORC1 ...

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ESPE Yearbook of Paediatric Endocrinology

Yearbook of Paediatric Endocrinology 2019

8. Adrenals

Clinical Trials - New Treatments

8.9. A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

8.10. Treatment of Primary Aldosteronism with mTORC1 Inhibitors

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