ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2019

9. Oncology and Chronic Disease

Biologic Agents and Growth in Chronic Inflammatory Diseases

ey0016.9-15 | Biologic Agents and Growth in Chronic Inflammatory Diseases | ESPEYB16

9.15. Growth during Tocilizumab therapy for Polyarticular-course juvenile idiopathic arthritis: 2-year data from a phase III clinical trial

KN Bharucha , HI Brunner , I Calvo Penades , I Nikishina , N Rubio-Perez , S Oliveira , K Kobusinska , H Schmeling , F Sztajnbok , F Weller-Heinemann , E Zholobova , F Zulian , R Allen , J Chaitow , J Frane , C Wells , N Ruperto , F De Benedetti

To read the full abstract: J Rheumatol. 2018; 45(8): 1173In recent years, biologic agents have clearly been shown to be effective in maintaining remission and improving linear growth in children with inflammatory bowel disease and other chronic inflammatory diseases (1–3). This prospective cohort study analyzed growth in 187 patients (143 females, mean age 11±4 years; including...