ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2019

11 Obesity and Weight Regulation

Brown Adipose Tissue: The Story Goes On

ey0016.11-10 | Brown Adipose Tissue: The Story Goes On | ESPEYB16

11.10. Brown adipose tissue in prepubertal children: associations with sex, birthweight, and metabolic profile

R Malpique , JM Gallego-Escuredo , G Sebastiani , J Villarroya , A Lopez-Bermejo , F de Zegher , F Villarroya , L Ibanez

To read the full abstract: Int J Obes 2019; 43(2): 384–91Studies regarding brown adipose tissue (BAT) activity in children are scarce due to the difficulties in detecting BAT by imaging and the need for elaborate techniques to measure BAT activity. Here, prepubertal children born small for gestational age (SGA, n=41) and children born appropriate for gestational age (AGA, <...

ey0016.11-11 | Brown Adipose Tissue: The Story Goes On | ESPEYB16

11.11. Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues

A Raajendiran , G Ooi , J Bayliss , PE O'Brien , RB Schittenhelm , AK Clark , RA Taylor , MS Rodeheffer , PR Burton , MJ Watt

To read the full abstract: Cell Rep 2019; 27(5): 1528–40These authors used FACS cell sorting, gene expression profiling, and metabolic and proteomic analyses to identify three distinct adipocyte progenitor cell (APCs) subtypes that reside in human white adipose tissues. Although they retain comparable differentiation capacity, they have different molecular profiles and give rise to ...