Body Weight and Appetite/Energy Regulation

ey0017.11-5 | Body Weight and Appetite/Energy Regulation | ESPEYB17

11.5. Appetite control is improved by acute increases in energy turnover at different levels of energy balance

FA Hagele , F Busing , A Nas , M Hasler , MJ Muller , Blundell JE , A Bosy-Westphal

To read the full abstract: J Clin Endocrinol Metab 2019;104(10):448191. PMID 31305927.In this randomized crossover study, 16 healthy adults were examined in a metabolic chamber during four different conditions of energy balance (ad libitum energy intake, zero energy balance, 25% caloric restriction, and 125% overfeeding) and at three levels of energy turnover (ET): Physi...

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ey0017.11-6 | Body Weight and Appetite/Energy Regulation | ESPEYB17

11.6. Leptin’s hunger-suppressing effects are mediated by the hypothalamic-pituitary-adrenocortical axis in rodents

RJ Perry , JM Resch , AM Douglass , JC Madara , A Rabin-Court , H Kucukdereli , C Wu , JD Song , BB Lowell , GI Shulman

To read the full abstract: Proc Natl Acad Sci U S A 2019;116(27):1367013679. doi: https://pubmed.ncbi.nlm.nih.gov/31213533/In this paper, Perry et al. studied several animal models to disentangle the mechanism by which leptin suppresses hunger. In rats, the hyperphagia induced by a 48 h fast, or a hypoglycemic hyperinsulinemic clamp, or uncontrolled diabetes, was completely s...

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ey0017.11-7 | Body Weight and Appetite/Energy Regulation | ESPEYB17

11.7. Leptin mediates postprandial increases in body temperature through hypothalamus-adrenal medulla-adipose tissue crosstalk

RJ Perry , K Lyu , A Rabin-Court , J Dong , X Li , Y Yang , H Qing , A Wang , X Yang , GI Shulman

To read the full abstract: J Clin Invest 2020;130(4):200116.In this study, Perry et al used their well-established animal model of fasted rats to unravel how feeding induces hyperthermia and energy expenditure.They showed that intracerebroventricular injection of leptin normalized fasting induced low plasma epinephrine and norepinephrine levels and body temperat...

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ESPE Yearbook of Paediatric Endocrinology

Yearbook of Paediatric Endocrinology 2020

11. Obesity and Weight Regulation

11.5. Appetite control is improved by acute increases in energy turnover at different levels of energy balance

11.6. Leptin’s hunger-suppressing effects are mediated by the hypothalamic-pituitary-adrenocortical axis in rodents

11.7. Leptin mediates postprandial increases in body temperature through hypothalamus-adrenal medulla-adipose tissue crosstalk

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