ESPE Yearbook of Paediatric Endocrinology

  Introduction: This section of the Year in Review continues to see important advances in our understanding the etiology of endocrinopathies and of pre- and post-natal growth disorders, including new gene variants, genomic associations, epigenetics and transcriptomics. New therapies continue to receive attention for rare diseases or conditions diagnosed in the fetus or infant, and more data is accruing on the impact of maternal medications during pregnancy – such as the GLP-1 agonists and metformin - on the fetus and newborn. Many of these excellent studies involve international collaborations, underlining the efficiency, progress, patient benefits and importance of global scientific efforts. As always, the choice was difficult.