ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Diabetes Care. 2017;40:1010-1016Professor Tamberlane and co-workers investigated the rates of severe hypoglycemia in the DCCT/Epidemiology of Diabetes Interventions and Complications (EDIC) cohort after approximately 30 years of follow-up. In earlier studies, high rates of hypoglycemic episodes had been found to be associated with lower HbA1c levels and intensified insulin ...

Brief Summary: This longitudinal observational study combined data from the SEARCH (T1D: N=564; T2D: N=149) and TODAY studies (T2D: N=495). Complications were higher in those with childhood onset T2D compared to T1D, with T2D showing 2.5 to 4 times higher rates of microvascular, macrovascular events despite similar diabetes duration. Risk factors for complications differed between T2D and T1D, with mean arterial pressure being a common predictor for both.<p class="abstext"...