ISSN 1662-4009 (online)

ESPE Yearbook of Paediatric Endocrinology (2018) 15 1.12 | DOI: 10.1530/ey.15.1.12

ESPEYB15 1 Pituitary and Neuroendocrinology Reviews (3 abstracts)

1.12 Growth hormone - past, present and future

Ranke MB & Wit JM


Department of Pediatric Endocrinology, University Children’s Hospital, Tubingen, Germany.
Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands


To read the full abstract: Nat Rev Endocrinol 2018;14:285-300

This is an interesting review of the history of research in the field of GH-IGF1 and the clinical use of GH. It comprises a timeline starting in 1884 with the description of dwarfism (General Tom Thumb) and gigantism, and ending in 2015-16 describing the discovery of paternally inherited IGF2 mutations and PAPPA-2 mutations as causes for short stature. This is a pleasure to read, and you are sure to learn something new.

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