ISSN 1662-4009 (online)

ESPE Yearbook of Paediatric Endocrinology (2018) 15 10.7 | DOI: 10.1530/ey.15.10.7

ESPEYB15 10 Type 1 Diabetes Mellitus Continuous glucose monitoring, insulin pumps and artificial pancreas (7 abstracts)

10.7 Closed-loop control during intense prolonged outdoor exercise in adolescents with T1DM: the artificial pancreas ski study

Breton MD , Cherñavvsky DR , Forlenza GP , DeBoer MD , Robic J , Wadwa RP , Messer LH , Kovatchev BP & Maahs DM


Center for Diabetes Technology, University of Virginia, Charlottesville, VA, USA


To read the full abstract: Diabetes Care. 2017;40:1644-1650

Exercise is thought to lead to more stable metabolic control but may also be associated with an increased risk of hypoglycemia. The selection of sport disciplines does not differ between youngsters with diabetes and their healthy siblings. Also, patients with diabetes are not restricted in respect to their sporting activities but seem to engage more vigorously in sports than their peers or siblings. Intensive winter sport activities such as alpine skiing pose an exceptional threat for hypoglycemia both because of the outdoor nature of the sport in cold temperature and the high intensity and long lasting character of the exercise. In this publication by Breton et al. the use of a closed-loop artificial pancreas system (CLC) in adolescents with T1DM actually improved glycemic control and reduced exposure to hypoglycemia during prolonged intensive winter sport activities, despite the added challenges of cold and altitude. This study clearly shows the feasability, safety and superiority of closed-loop insulin delivery system over conventional insulin therapy under real-time, practical, day-to-day challenges of adolescents. The time of the artificial pancreas is here!

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