ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
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Yearbook of Paediatric Endocrinology 2021

11. Obesity and Weight Regulation

New insight into preconceptional and prenatal programming

Previous section
Criticism of the previous BMI metrics for use in severely obese children
Table of contents

ey0018.11-13 | New insight into preconceptional and prenatal programming | ESPEYB18

11.13. Associations between exposure to gestational diabetes mellitus in utero and daily energy intake, brain responses to food cues, and adiposity in children

S Luo , BC Angelo , T Chow , JR Monterosso , PM Thompson , AH Xiang , KA Page

Diabetes Care. 2021 May;44(5):1185–1193. 10.2337/dc20-3006. https://pubmed.ncbi.nlm.nih.gov/33827804/Luo et al. performed a retrospective cohort study of 159 children (age 7–11 years), including undertaking a food cue task while in the MRI scanner, to investigate whether brain reward systems are altered by in utero exposure to ...
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ey0018.11-14 | New insight into preconceptional and prenatal programming | ESPEYB18

11.14. Lifestyle intervention in pregnant women with obesity impacts cord blood DNA methylation, which associates with body composition in the offspring

J Jonsson , KM Renault , S Garcia-Calzon , A Perfilyev , AC Estampador , K Norgaard , M Vendelbo Lind , A Vaag , L Hjort , KF Michaelsen , E Malchau Carlsen , PW Franks , C Ling

Diabetes 2021 Apr;70(4):854–866. https://pubmed.ncbi.nlm.nih.gov/33431374/These authors performed a randomized trial of obese pregnant women (n=425) to investigate the effects of a pregnancy lifestyle intervention on epigenetic variations in umbilical cord blood, on neonatal body composition (DXA) and on offspring BMI in later life (up to 3 years). Offspring of mothers who re...
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ey0018.11-15 | New insight into preconceptional and prenatal programming | ESPEYB18

11.15. Sex-specific programming effects of parental obesity in pre-implantation embryonic development

K Hedegger , J Philippou-Massier , S Krebs , H Blum , S Kunzelmann , K Forstemann , M Gimpfl , AA Roscher , R Ensenauer , E Wolf , M Dahlhoff

Int J Obes (Lond). 2020 May;44(5):1185–1190. https://pubmed.ncbi.nlm.nih.gov/31776435/These authors investigated the effect of maternal and paternal obesity on gene expression level in the mouse blastocyst. Firstly, they show that female and male offspring were differentially sensitive to an obesogenic maternal environment in the early phase of preimplantation. Male blastocysts from o...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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