ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2021

6. Differences of Sexual Development (DSD) and Gender Dysphoria (GD)

Longterm Effects of Hormonal Treatments in Gender Dysphoria

ey0018.6-14 | Longterm Effects of Hormonal Treatments in Gender Dysphoria | ESPEYB18

6.14. Thrombosis Risk in Transgender Adolescents Receiving Gender-Affirming Hormone Therapy

ES Mullins , R Geer , M Metcalf , J Piccola , A Lane , LAE Conard , TLK Mullins

Pediatrics. 2021 Mar 22:e2020023549. doi: 10.1542/peds.2020-023549. PMID: 33753543.This retrospective, single center chart review study assessed the incidence of arterial or venous thrombosis during gender affirming hormone therapy (GAHT) in 611 transgender adolescents. The prevalence of thrombosis risk factors was also investigated. No increased risk of thrombosis was found over a short ...

ey0018.6-15 | Longterm Effects of Hormonal Treatments in Gender Dysphoria | ESPEYB18

6.15. Development of Hip Bone Geometry During Gender-Affirming Hormone Therapy in Transgender Adolescents Resembles That of the Experienced Gender When Pubertal Suspension Is Started in Early Puberty

MA van der Loos , I Hellinga , MC Vlot , DT Klink , M den Heijer , CM Wiepjes

J Bone Miner Res. 2021 May;36(5):931–941. doi: 10.1002/jbmr.4262. PMID: 33507568.This restrospective study of the Cohort of Gender Dysphoria investigated bone geometry parameters of 106 adolescent trans-women and 216 adolescent trans-men during early and late start of gonadotropin-releasing hormone agonist (GnRHa) and gender affirming hormone therapy (GAHT). Transgender youth who started tr...

ey0018.6-16 | Longterm Effects of Hormonal Treatments in Gender Dysphoria | ESPEYB18

6.16. Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study

A Weill , P Nguyen , M Labidi , B Cadier , T Passeri , L Duranteau , AL Bernat , I Yoldjian , S Fontanel , S Froelich , J Coste

BMJ. 2021 Feb 3;372:n37. doi: 10.1136/bmj.n37. PMID: 33536184This observational cohort study used data from the French administrative healthcare database during 2007–2015 to assess the risk of meningioma development related to treatment with cyproterone acetate. The cohort comprised 253,777 participants, of whom 54% had high exposure to cyproterone acetate, and 45% had low exposure.<p cla...