ISSN 1662-4009 (online)

ESPE Yearbook of Paediatric Endocrinology (2021) 18 2.2 | DOI: 10.1530/ey.18.2.2

ESPEYB18 2. Antenatal and Neonatal Endocrinology Neonatal hypoglycaemia (7 abstracts)

2.2. Accuracy of continuous glucose monitoring in preterm infants: a systematic review and meta-analysis.

Nava C , Modiano Hedenmalm A , Borys F , Hooft L , Bruschettini M & Jenniskens K

BMJ Open. 2020 Dec 24;10(12):e045335. doi: 10.1136/bmjopen-2020-045335. PMID: 33361084

This BMJ review aimed to assess the accuracy of CGM devices to detect hypoglycaemia and hyperglycaemia in preterm infants. The key take home messages from the BMJ review were that the sensitivity for CGM devices to diagnose and detect hypoglycaemia in preterm infants was poor but the specificity was high. On the other hand, the sensitivity and specificity for CGM devices to diagnose and detect hyperglycaemia were high.

Thus, CGM devices will not correctly detect all episodes of hypoglycaemia and should therefore be supplemented with additional measures for glucose monitoring. CGM devices can be used to monitor trends of blood glucose in these preterm infants. Several technological issues (1) will need to be addressed before CGM devices can be recommended for routine glucose monitoring in neonatal intensive care units.

Reference: 1. McKinlay CJD, Chase JG, Dickson J, Harris DL, Alsweiler JM, Harding JE. Continuous glucose monitoring in neonates: a review. Maternal Health Neonatol Perinatol. 2017 Oct 17;3:18.

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