ISSN 1662-4009 (online)

Previous issue | Volume 19 | ESPEYB19 | Next issue

Yearbook of Paediatric Endocrinology 2022

ey0019.14-17 | Reviews | ESPEYB19

14.17. Prevention of atherosclerosis from childhood

Raitakari Olli , Pahkala Katja , Magnussen Costan G

Nat Rev Cardiol. 2022, 19(8):543-554. doi: 10.1038/s41569-021-00647-9This review discusses the role of apo-lipoprotein B (apoB)-containing lipoproteins (commonly estimated by LDL cholesterol) in the process of atherosclerosis throughout the life-course. The authors comprehensively describe the development of atherosclerosis according to the response-to-retention hypothesis, and they presen...

ey0019.14-18 | Reviews | ESPEYB19

14.18. Endocrine manifestations and new developments in mitochondrial disease

Ng Yi Shiau , Lim Albert Zishen , Panagiotou Grigorios , Turnbull Doug M , Walker Mark

Endocr Rev. 2021 Oct 13;bnab036. PMID: 34644386 doi: 10.1210/endrev/bnab036Brief Summary: This comprehensive review summarizes the current knowledge on the spectrum of endocrine disorders associated with mitochondrial disease. It provides essential information on the basics and genetics of mitochondrial diseases and details the clinical characteristics, focusing on endocrine and important non-...

ey0019.14-19 | Reviews | ESPEYB19

14.19. Cytoplasmic DNA: sources, sensing, and role in aging and disease

Miller Karl N , Victorelli Stella G , Salmonowicz Hanna , Dasgupta Nirmalya , Liu Tianhui , Passos Joao F , Adams Peter D

Cell. 2021 Oct 28;184(22):5506–5526. doi: 10.1016/j.cell.2021.09.034Brief Summary: The authors review the function and the underlying molecular mechanisms of 4 major species of endogenous cytoplasmic DNA (cytoDNA) in the development of chronic ageing-associated diseases.In the presence of foreign DNA (e.g. viral infections), innate immunity acts as a defence mec...