ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
Previous issue | Volume 20 | ESPEYB20

Yearbook of Paediatric Endocrinology 2023

1. Thyroid

Follow-up Paper from the 2022 Yearbook

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Thyroid Development
Table of contents
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Congenital Hypothyroidism

ey0020.1-5 | Follow-up Paper from the 2022 Yearbook | ESPEYB20

1.5. Evaluation of the molecular landscape of pediatric thyroid nodules and use of a multigene genomic classifier in children

JN Gallant , SC Chen , CA Ortega , SL Rohde , RH Belcher , JL Netterville , N Baregamian , H Wang , J Liang , F Ye , YE Nikiforov , MN Nikiforova , VL Weiss

Brief summary: In 2021 and 2022, two important publications on pediatric thyroid carcinomas revealed a distinct molecular landscape compared to adult thyroid carcinomas (1,2). Pediatric differentiated thyroid carcinoma was mainly caused by fusion oncogenes, especially in children younger than 10 years (93%), compared to children aged 10–15 years (28%) and 15–20 years old patients (14%). In contrast, PTC due to BRAF mutations showed increasing frequency with age (7%, ...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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