ISSN 1662-4009 (online)

ey0016.8-15 | New Concerns | ESPEYB16

8.15. Epigenetic alterations associated with early prenatal dexamethasone treatment

L Karlsson , M Barbaro , E Ewing , D Gomez-Cabrero , S Lajic

To read the full abstract: J Endocr Soc. 2018; 3(1): 250–263.Prenatal treatment with dexamethasone (DEX) has been used to avoid virilization in girls with Congenital Adrenal Hyperplasia (CAH). However, it has potential short- and long-term risks and has been associated with cognitive impairments. Here, the authors investigate whether epigenetic modification of DNA during early devel...