ESPE Yearbook of Paediatric Endocrinology

Brief summary: This paper reviews the incidence of congenital adrenal hyperplasia (CAH) across 58 studies (31 countries). The overall CAH incidence was 1:9498. Geographic variation was observed with a higher incidence in Eastern Mediterranean and South-East Asia and a lower incidence in countries of the Western Pacific region.Untreated CAH is a recessive condition associated with high mortality and morbidity and early diagnosis and management are key. Un...

Brief summary: An analysis of contraception data in 204 countries and territories between 1970 and 2019 shows that 162.9 million women had unmet needs for contraception (65.5% in sub-Saharan Africa and in south Asia). Demand was not satisfied for 64.8% of women aged 15–19 years, the highest proportion of any age group.This study included women aged 15–49 years and analysed contraceptive prevalence rate (CPR) and ‘demand satisfied’. We...

Brief summary: This cross-sectional study found high prevalences of high dietary intakes of fat and sugar and inadequate intakes of fiber among obese Indonesian adolescents, and a statistically significant correlation between fiber intake and HDL cholesterol levels.Low and middle-income countries are experiencing nutritional transitions with increasing prevalence of obesity and cardiovascular disease risks. This cross-sectional study performed in Indones...

Brief summary: This study describes the genetic and clinical characteristics of 3βHSD2 deficiency in children seen at a single center in Algeria. It describes clinical outcomes, including the frequency of adrenal rest tumors in this population.3β-hydroxysteroid dehydrogenase 2 deficiency (3βHSD2) is a rare form of congenital adrenal hyperplasia. This mixed longitudinal and cross-sectional study was performed in a single Algerian center bet...

Brief summary: This case series of five patients with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH) treated in Damascus, Syria is presented to highlight the current management, including the difficulties of sex assignment, in this cultural context.In Syria, female infants with 21-hydroxylase deficiency CAH and resulting virilization are generally considered to be male until proven otherwise. This case series reports on the care of five c...

Brief summary: This retrospective study describes patients diagnosed with delayed puberty in a single tertiary care center in Sudan. The frequencies of various etiologies of delayed puberty are described.Delayed puberty is a common cause for referral to endocrinology clinics, usually due to concerns about height or future fertility. This retrospective study summarises the characteristics of patients with delayed puberty seen in the endocrinology unit at ...