Abstract Search

10.9. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study

ME Miettinen , S Niinisto , I Erlund , D Cuthbertson , AM Nucci , J Honkanen , O Vaarala , H Hyoty , JP Krischer , M Knip

Diabetologia. 2020;63(4):780787. doi: 10.1007/s00125-019-05077-4.This multicenter multinational study, in children with high genetic risk of T1D, identified an association between lower serum 25-hydroxyvitamin D (25OHD) concentrations and subsequent appearance of islet autoimmunity or T1D.The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) ancillary ...

0 shares

ey0015.10-20 | Prevention | ESPEYB15

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

Writing Group for the TRIGR Study Group , M Knip , HK Åkerblom , E Al Taji , D Becker , J Bruining , L Castano , T Danne , C de Beaufort , HM Dosch , J Dupre , WD Fraser , N Howard , J Ilonen , D Konrad , O Kordonouri , JP Krischer , ML Lawson , J Ludvigsson , L Madacsy , JL Mahon , A Ormisson , JP Palmer , P Pozzilli , E Savilahti , M Serrano-Rios , M Songini , S Taback , Vaarala , NH White , SM Virtanen , R Wasikowa

To read the full abstract: JAMA. 2018;319:38-48Earlier observational studies showed that dietary exposure to complex proteins in newborns and early infants is associated with beta cell autoimmunity and increase the risk for T1DM. Several studies avoiding certain proteins, such as gluten and casein, have been conducted without reducing the risk for T1D in genetically susceptible children. Theref...

0 shares

ESPE Yearbook of Paediatric Endocrinology

10.9. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

BiosciAbstracts