ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

15 Editor’s Choice

Memories that persist into adulthood

ey0015.15-14 | Memories that persist into adulthood | ESPEYB15

15.14 Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood

X Yuan , K Tsujimoto , K Hashimoto , K Kawahori , N Hanzawa , M Hamaguchi , T Seki , M Nawa , T Ehara , Y Kitamura

To read the full abstract: Nature Communications 2018;9:636We know that good nutrition early in life has profound and long-lasting effects on body weight in later life. Malnutrition during pregnancy or infant formula feeding may be stored on the offspring genome as epigenetic memory and persist into adulthood, thereby influencing the susceptibility to metabolic diseases, such as obes...