ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018

5 Bone, Growth Plate and Mineral Metabolism

Growth velocity as a laboratory parameter

ey0015.5-10 | Growth velocity as a laboratory parameter | ESPEYB15

5.10 A degradation fragment of type X collagen is a real-time marker for bone growth velocity

RF Coghlan , JA Oberdorf , S Sienko , MD Aiona , BA Boston , KJ Connelly , C Bahney , J LaRouche , SM Almubarak , DT Coleman , I Girkontaite , K von der Mark , GP Lunstrum , WA Horton

To read the full abstract: Sci Transl Med 2017;9(419)Can growth velocity be monitored by a lab test? Previous approaches to this methodological challenge focused on the correlation of linear growth to more established parameters such as C-type natriuretic peptide (CNP). Potentially more specific markers of endochondral ossification - with the exception of amino-terminal propeptide of CNP (...