ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018


Genetic variants and timing of puberty

ey0015.7-6 | Genetic variants and timing of puberty | ESPEYB15

7.6 Differential Impact of Genetic Loci on Age at Thelarche and Menarche in Healthy Girls

AS Busch , CP Hagen , M Assens , KM Main , K Almstrup , A Juul

To read the full abstract: J Clin Endocrinol Metab. 2018 Jan 1;103(1):228-234[Comments on 7.5 and 7.6] Remarkably, the timing of puberty shows important differences between individuals1. Based on twin studies, differences in pubertal timing are considered to depend on genetic factors which account for up to 60-70% of the varianc...