ISSN 1662-4009 (online)

Volume 15 | ESPEYB15 | Next issue

Yearbook of Paediatric Endocrinology 2018


New concept: Epigenetic control of puberty

ey0015.7-1 | New concept: Epigenetic control of puberty | ESPEYB15

7.1 Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty

CA Toro , H Wright , CF Aylwin , SR Ojeda , A Lomniczi

To read the full abstract: Nat Commun. 2018 Jan 4;9(1):57The hypothalamic-pituitary-gonadal axis controls the onset of puberty and the acquisition of the reproductive function. A subset of neurons in the anterior hypothalamus secretes gonadotropin-releasing hormone (GnRH) which, through its pattern of release controls all aspects of reproduction throughout life. The secretory activity of GnR...