ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica
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Yearbook of Paediatric Endocrinology 2021

11. Obesity and Weight Regulation

New hope: Increased diagnostic yield for disease causing MC4R variants and pharmacological treatment options

Previous section
The COVID 19 pandemic and obesity
Table of contents
Next section
New insight: neurobiology and weight regulation

ey0018.11-2 | New hope: Increased diagnostic yield for disease causing MC4R variants and pharmacological treatment options

11.2. Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signalling

ey0018.11-3 | New hope: Increased diagnostic yield for disease causing MC4R variants and pharmacological treatment options

11.3. Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

ey0018.11-4 | New hope: Increased diagnostic yield for disease causing MC4R variants and pharmacological treatment options

11.4. Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

ey0018.11-5 | New hope: Increased diagnostic yield for disease causing MC4R variants and pharmacological treatment options

11.5. Obesity treatment effect in danish children and adolescents carrying melanocortin-4 receptor mutations

Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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