ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2021

ey0018.2-23 | Miscellaneous | ESPEYB18

2.23. Maternal organophosphate flame-retardant exposure alters offspring energy and glucose homeostasis in a sexually dimorphic manner in mice

SN Walley , EA Krumm , A Yasrebi , J Kwiecinski , V Wright , C Baker , TA Roepke

J Appl Toxicol. 2021 Apr;41(4):572–586. doi: 10.1002/jat.4066. PMID: 329695In this study, pregnant dams were exposed to different types of organophosphate flame retardants (OPFRs) at a sensitive development period (from gestation to lactation). The offspring were fed either a high or a low-fat diet for 17 weeks and then underwent a battery of metabolic assessments. OPFR exposure did not alte...