ISSN 1662-4009 (online)

Previous issue | Volume 19 | ESPEYB19 | Next issue

Yearbook of Paediatric Endocrinology 2022

ey0019.12-6 | Metabolic syndrome | ESPEYB19

12.6. Abuse in childhood and cardiometabolic health in early adulthood: evidence from the Avon longitudinal study of parents and children

A Goncalves Soares A, Zimmerman A, Zammit S, Karl A, Halligan SL, Fraser

Journal of the American Heart Association 2021;10(24):e021701. doi: 10.1161/JAHA.121.021701Brief Summary: This population-based birth cohort study identified an association between childhood abuse and higher BMI at age 18 and 25 years, and also hyperinsulinemia and other markers of the MetS at age 25.Comment: Previous studies reported that about one-third of adult candi...

ey0019.12-7 | Metabolic syndrome | ESPEYB19

12.7. Serum ferritin and the risk of metabolic syndrome: a systematic review and dose-response meta-analysis of cross-sectional studies

B. Zhang WCB, Xing Y, Shao

Biomedical and Environmental Sciences, 2021, 34(8): 623–631 doi: 10.3967/bes2021.086Brief Summary: This cross-sectional study identified associations between serum ferritin levels with dyslipidemia and the MetS in both adult men and women. In addition, significant associations were found for ferritin levels with the risks of insulin resistance, prediabetes and T2DM in women.<p class="abs...

ey0019.12-8 | Metabolic syndrome | ESPEYB19

12.8. “Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis

M. Febbraio MA, Karin

Cell metabolism 2021;33(12):2316-28. doi: 10.1016/j.cmet.2021.09.004Brief Summary: This paper reviews the links between fructose consumption and health, and the mechanisms by which fructose may damage health.Comment: Fructose is a plant-derived monosaccharide. Its natural form is found in certain fruits and vegetables. High-fructose corn syrup (HFCS) is a liquid fruc...

ey0019.12-9 | Metabolic syndrome | ESPEYB19

12.9. Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus

BN Ferguson D, Finck

Nat Rev Endocrinol 2021;17(8):484-95. doi: 10.1038/s41574-021-00507-zBrief Summary: This article reviews the results of clinical trials for modulators of glucagon-like peptide-1 (GLP1) activity, insulin-sensitizing thiazolidinediones, and inhibitors of the sodium-glucose cotransporter 2 (SGLT2) for the treatment of NAFLD and type 2 diabetes mellitus.Comment: NAFLD ha...

ey0019.12-10 | Metabolic syndrome | ESPEYB19

12.10. Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

P. Sato S, Dyar KA, Treebak JT, Jepsen SL, Ehrlich AM, Ashcroft SP, Trost K, Kunzke T, Prade VM, Small L, Basse AL, Schonke M, Chen S, Samad M, Baldi P, Barres R, Walch A, Moritz T, Holst JJ, Lutter D, Zierath JR, Sassone-Corsi

Cell metabolism 2022;34(2):329-45.e8. doi: 10.1016/j.cmet.2021.12.016Brief Summary: In a mouse model, time of exercise during the day was found to determine the magnitude and type of metabolic response. Different tissues responded to exercise at different times of the day.Comment: Exercise is considered a vital intervention in the prevention and treatment of individu...