ISSN 1662-4009 (online)

Previous issue | Volume 19 | ESPEYB19 | Next issue

Yearbook of Paediatric Endocrinology 2022

14. Science and Medicine

Risk and Outcome

ey0019.14-8 | Risk and Outcome | ESPEYB19

14.8. Development over time of the population-attributable risk fraction for cannabis use disorder in schizophrenia in Denmark

Hjorthoj Carsten , Posselt Christine Merrild , Nordentoft Merete

JAMA Psychiatry. 2021 Sep 1;78(9):1013–1019. PMID: 34287621. doi: 10.1001/jamapsychiatry.2021.1471. Summary: This nationwide prospective registry study from Denmark in >7 million individuals reports that the proportion of ...

ey0019.14-9 | Risk and Outcome | ESPEYB19

14.9. A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk

SA Williams , R Ostroff , MA Hinterberg , J Coresh , CM Ballantyne , K Matsushita , CE Mueller , J Walter , C Jonasson , RR Holman , SH Shah , N Sattar , R Taylor , ME Lean , S Kato , H Shimokawa , Y Sakata , K Nochioka , CR Parikh , SG Coca , T Omland , J Chadwick , D Astling , Y Hagar , N Kureshi , K Loupy , C Paterson , J Primus , M Simpson , NP Trujillo , P Ganz

Sci Transl Med. 2022 Apr 6;14(639):eabj9625; PMID 35385337 doi: 10.1126/scitranslmed.abj9625 Summary: This international study, led by Dr. Stephens Williams from Boulder, Colorado, USA, developed a surrogate biomarker from 27 circulating proteins to predict ...

ey0019.14-10 | Risk and Outcome | ESPEYB19

14.10. Childhood cardiovascular risk factors and adult cardiovascular events

DR Jr Jacobs , JG Woo , AR Sinaiko , SR Daniels , J Ikonen , M Juonala , N Kartiosuo , T Lehtimaki , CG Magnussen , JSA Viikari , N Zhang , LA Bazzano , TL Burns , RJ Prineas , J Steinberger , EM Urbina , AJ Venn , OT Raitakari , T Dwyer

N Engl J Med. 2022 May 19;386(20):1877–1888. doi: 10.1056/NEJMoa2109191.Brief summary: This prospective cohort study leveraged data from the International Childhood Cardiovascular Cohorts (i3C) Consortium, including 42 324 participants at baseline and followed-up over a mean of 35 years, in order to investigate associations between cardiovascular risk factors (CVRF, including body-mass ind...

ey0019.14-11 | Risk and Outcome | ESPEYB19

14.11. SGA-born adults with postnatal catch-up have a persistently unfavourable metabolic health profile and increased adiposity at age 32 years

Goedegebuure Wesley J. , Van der Steen Manouk , Smeets Carolina CJ , Kerkhof Gerthe F , Hokken-Koelega Anita CS

European Journal of Endocrinology (2022)187:15–26 doi: 10.1530/EJE-21-1130Brief Summary: This study, PROGRAM32, investigated 287 adults mean age 32 years who had participated 10 years earlier in the PROGRAM study on the metabolic and cardiovascular consequences of low birth weight (LBW). The aim was to investigate the adverse metabolic profile of being small for gestational age with spontane...

ey0019.14-12 | Risk and Outcome | ESPEYB19

14.12. Smoking during pregnancy is associated with child overweight independent of maternal pre-pregnancy BMI and genetic predisposition to adiposity

Schnurr Theresia M , Angquist Lars , Nohr Ellen Aagaard , Hansen Torben , Sorensen Thorkild I.A. , Morgen Camilla S

Scientific Reports (2022)12:3135 doi: 10.1038/s41598-022-07122-6Brief Summary: This case cohort study, based on the Danish National Birth Cohort (DNBC) with ~100 000 women and their children, investigated whether maternal smoking in pregnancy is associated with child BMI and risk for child overweight, independent of maternal pre-pregnancy BMI, genetic predisposition to adiposity and socio-...