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Yearbook of Paediatric Endocrinology 2022

8. Adrenals

Mechanism of the year: neuropeptide substance P regulates aldosterone secretion

ey0019.8-1 | Mechanism of the year: neuropeptide substance P regulates aldosterone secretion | ESPEYB19

8.1. The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys

K Cheng , Y Seita , T Moriwaki , K Noshiro , Y Sakata , YS Hwang , T Torigoe , M Saitou , H Tsuchiya , C Iwatani , M Hosaka , T Ohkouchi , H Watari , T Umazume , K Sasaki

Sci Adv. 2022; 8(16): eabn8485. PMID: 35442744https://pubmed.ncbi.nlm.nih.gov/35442744/Brief Summary: This histologic and transcriptomic study of human and primate adrenal tissue samples provides a molecular framework to understand the fetal development of the adrenal gland.The adrenal cortex is the major source of steroid hormones that drive a plethora of critical ph...