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ey0016.5-15 | Basic Science - Growth Plate | ESPEYB16

5.15. mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats

YH Jee , J Wang , S Yue , M Jennings , SJ Clokie , O Nilsson , JC Lui , J Baron

Abstract: Endocrinology. 2018 Mar 1;159(3):14691478.In brief: In this article, a combination of microdissection, miroRNA profiling and transfection studies identify 3 microRNAs that are highly expressed in the proliferative zone and appear to be down-stream mediators of PTHrP signaling in the growth plate.Comment: In the growth plate, P...

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ey0016.5-13 | Basic Science - Growth Plate | ESPEYB16

5.13. Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

JC Lui , YH Jee , P Garrison , JR Iben , S Yue , M Ad , Q Nguyen , B Kikani , Y Wakabayashi , J Baron

Abstract: PLoS Biol. 2018 Jul 23;16(7):e2005263.In brief: In this article, Lui et al, make important observations related to the fundamental limits of longitudinal bone growth implicating the growth plate senescence program as a major regulator of bone size.Comment: A persons right and left arms almost always grow to the same length, bu...

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ESPE Yearbook of Paediatric Endocrinology

5.15. mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats

5.13. Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

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