ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Endocr Pract 2018;24:565-572.Summary: According to this retrospective chart review of 34 transgender men, testosterone therapy in this population, across a wide range of doses and over many years, did not result in the profile of dyslipidemia and dysglycemia that is observed in women with polycystic ovary syndrome (PCOS). Instead, treatment of transgend...

Lancet Diabetes Endocrinol 2019 Published Online March 13, 2019. DOI: 10.1016/S2213-8587(19)30083-X• Practical challenges associated with diabetes care in humanitarian contexts in low- and middle- income countries abound.• In this position paper, the authors articulate the important needs around diabetes care in the context of the 6 building blocks ...

To read the full abstract: Pediatrics. 2018 Apr;141(4)See comment on 6.8....

To read the full abstract: J Adolesc Health. 2017 Jul;61(1):120-123Recent developments in assisted reproduction technologies (ART) have changed the scene for fertility wishes in a number of disorders, including GD. Fertility preservation is now routinely offered to postpubertal adolescent and adult GD patients at increasing numbers of medical centers. For biological boys, this is a non...

Ze’ev Hochberg was fascinated by growth, a dominant topic during his long-standing career. He published 153 articles on growth according to PubMed, the first 1980 [1] and the last in April this year [2]. Synergy between thyroid hormones and growth hormone was recognized decades ago [3] but Ze’ev Hochberg added an important piece of knowledge on the impact of hypothyroidism on the growth plate as well as the effects of thyroid hormones, growth hormone and the combinat...

Pediatr Diabetes 2020;1–8. doi: 10.1111/pedi.13137– As part of the SWEET initiative, the authors analyzed the clinical characteristics of 26,726 individuals with type 1 diabetes (T1D) aged < 21 years living in Europe, Asia/Middle East/Africa, Australia/New Zealand, North America and South America– Among patient care indicators, the percent of HbA1c < 7.5% ranged between r...

Pediatr Nephrol, 2022. 37(4): p. 859-869 PMID: 34542703Brief Summary: This prospective observational cohort study investigated growth rate after kidney transplant in children with chronic kidney disease (CKD) and growth failure, who received or did not receive rhGH treatment before transplantation. Patients pre-treated with rhGH showed better growth rates with taller height SDS at 7 years after transplantation. Positive effects of pre-transplant...

J Bone Miner Res. 2021 Aug;36(8):1594-1604.Abstract: https://pubmed-ncbi-nlm-nih-gov/33900645/In Brief: Enzyme replacement therapy with human ENPP1-Fc protein in Enpp1asj/asj mice, a murine model of ENPP1 deficiency, restored circulating levels of PPi, prevented clinical manifestations and decreased mortality.Commentary: ENPP1 deficiency causes gen...

To read the full abstract: Environmental health perspectives vol. 127,10 (2019): 107011. doi: https://ehp.niehs.nih.gov/doi/full/10.1289/EHP5570?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmedThis study identifies the effects of exposure to environmentally rel...

To read the full abstract: Support Care Cancer. 2020 Feb 11. Epub ahead of print. hess2@phoenixchildrens.comThe development of a second neoplasia is a major concern during the follow-up of childhood cancer survivors (CCS). Secondary cancers account for nearly 50% of non-relapse mortality at 5 years. Thyroid tumours represent 10-20% of subsequent neoplasia cases, due to the high sensitivity of the g...