ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2019

8. Adrenals

Food for Thought

ey0016.8-19 | Food for Thought | ESPEYB16

8.19. Placental H3K27me3 establishes female resilience to prenatal insults

BM Nugent , CM O'Donnell , CN Epperson , TL Bale

Nat Commun. 2018; 9(1): 2555. doi: 10.1038/s41467-018-04992-1. differences in human disease have been extensively described for some of the most prevalent health conditions affecting societies today, from hypertension to diabetes, arthritis, and can...

ey0016.8-20 | Food for Thought | ESPEYB16

8.20. Associations of prenatal depressive symptoms with DNA methylation of HPA axis-related genes and diurnal cortisol profiles in primary school-aged children

V Stonawski , S Frey , Y Golub , N Rohleder , J Kriebel , TW Goecke , PA Fasching , MW Beckmann , J Kornhuber , O Kratz , GH Moll , H Heinrich , A Eichler

To read the full abstract: De Psychopathol. 2019; 31(2): 419–431.Environmental stimuli, especially in the pre- and postnatal periods, can have long-lasting effects on offspring development and health. Prenatal exposure to maternal depression, anxiety or stress may alter functioning of the hypothalamic-pituitary-adrenal (HPA) axis. Here, epigenetic modifications of DNA in genes...