ISSN 1662-4009 (online)

ey0015.13-8 | Type 1 and Type 2 Diabetes in Resource-Limited Settings | ESPEYB15

13.8 Developmental Origins of Health and Disease: the relevance to developing nations

M Mandy , M Nyirenda

To read the full abstract: Int Health 2018; 10; 66-70This article summarizes the concept of Developmental Origins of Health and Disease (DOHaD) and emphasizes its potential relevance to the marked increase in non-communicable diseases, including Type 2 diabetes, observed in low-resource settings. This is an important topic as the DOHaD concept may be a strong contributing factor to the develop...

ey0019.12-8 | Metabolic syndrome | ESPEYB19

12.8. “Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis

M. Febbraio MA, Karin

Cell metabolism 2021;33(12):2316-28. doi: 10.1016/j.cmet.2021.09.004Brief Summary: This paper reviews the links between fructose consumption and health, and the mechanisms by which fructose may damage health.Comment: Fructose is a plant-derived monosaccharide. Its natural form is found in certain fruits and vegetables. High-fructose corn syrup (HFCS) is a liquid fruc...

ey0015.9-10 | Growth, growth hormone and puberty in chronic diseases: novel insights from clinical practice | ESPEYB15

9.10 Pubertal development in children with chronic kidney disease

D Haffner , M Zivicnjak

To read the full abstract: Pediatr Nephrol. 2017;32:949-964This is a comprehensive review on growth and sexual maturation during puberty in children with chronic kidney disease (CKD). Despite attention to preserve growth potential during pre-puberty and the availability of recombinant human growth hormone (rhGH), the achievement of normal pubertal height gain remains a challenge in CKD. In pr...

ey0020.14-5 | Section | ESPEYB20

14.5. Emerging adulthood, a pre-adult life-history stage

Z Hochberg , M Konner

Brief summary: This review uses an evolutionary approach to provide an interesting discussion on a proposed period of development called ‘emerging adulthood’. The authors explain that it can be seen not only as a sociological transition period but also as a biological life-history phase.The central theme of this review is ‘emerging adulthood’, which is the concept that an additional 4-6-year pre-adult period should be included in mode...

ey0017.7-3 | Clinical Guidance | ESPEYB17

7.3. Pubertal timing and adult fracture risk in men: A population-based cohort study

L Vandenput , JM Kindblom , M Bygdell , M Nethander , C Ohlsson

To read the full abstract: PLoS Medicine vol. 16,12 e1002986. 2 Dec. 2019. doi: large scale population-based cohort study identifies a slightly higher risk for adult fracture in men who had later puberty. The pubertal period plays a key role...

ey0019.3-3 | Thyroid hormone action | ESPEYB19

3.3. Extended absorption of liothyronine from poly-zinc-liothyronine: results from a phase 1, double-blind, randomized, and controlled study in humans

AM Dumitrescu , EC Hanlon , M Arosemena , O Duchon , M Ettleson , M Giurcanu , AC Bianco

Thyroid. 2022 Feb;32(2):196-205. doi: 10.1089/thy.2021.0304. Epub 2021 Dec 31. PMID: 34641706Brief Summary: This phase 1, double-blind, randomized, single-dose, placebo-controlled, crossover study compared pharmacokinetics, pharmacodynamics, incidence of adverse events, and sleep pattern between the routinely used L-triiodothyronine (LT3) and a newly developed metal-coordinated form of LT3 (pol...

ey0017.15-3 | (1) | ESPEYB17

15.3. An association between maternal weight change in the year before pregnancy and infant birth weight: ELFE, a French national birth cohort study

M Lecorguille , M Jacota , B de Lauzon-Guillain , A Forhan , M Cheminat , MA Charles , B Heude

To read the full abstract: PLoS Med. 2019 Aug 20;16(8):e1002871. doi: 10.1371/journal.pmed.1002871.Women (n =16,395; 26% overweight or obese) from the ELFE French national birth cohort were categorised into 3 groups by self-reported weight change during the year before pregnancy: weight loss >5 kg; stable weight; and weight gain >5 kg.Among women with B...

ey0015.9-9 | Growth, growth hormone and puberty in chronic diseases: novel insights from clinical practice | ESPEYB15

9.9 Growth hormone treatment improves final height and nutritional status of children with chronic kidney disease and growth deceleration

C Bizzarri , A Lonero , M Delvecchio , L Cavallo , MF Faienza , M Giordano , L Dello Strologo , M Cappa

To read the full abstract: J Endocrinol Invest. 2018;41:325-331Growth failure is common in children with chronic kidney disease (CKD) and has a multifactorial etiology. The hypothalamus-pituitary axis is intact, but there is a resistance to growth hormone (GH) action in target tissues, secondary to decreased density of GH receptors, impaired signal transduction and reduced levels of free insu...