ISSN 1662-4009 (online)

Previous issue | Volume 17 | ESPEYB17

Yearbook of Paediatric Endocrinology 2020

11. Obesity and Weight Regulation

New Genetic Findings

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension
NRS UMR 8199, European Genomic Institute for Diabetes, Institut Pasteur de Lille, University of Lille, Lille, France;
Department of Metabolism, Section of Genomics of Common Disease, Imperial College London, London UK. p.froguel@imperial.ac.uk
ey0017.11-2
Human gain-of-function MC4R variants show signaling bias and protect against obesity
University of Cambridge MRC Epidemiology Unit, Welcome Trust-MRC Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK, luca.lotta@mrc-epid.cam.ac.uk
ey0017.11-3